Article
Differential gene expression in patients genetically predisposed to pancreatic cancer.
The Journal of surgical research - 1 Oct 2006
Zervos Emmanuel E, Tanner Stephan M, Osborne Dana A, Bloomston Mark, Rosemurgy Alexander S, Ellison E Christopher, Melvin W Scott, de la Chapelle Albert
Abstract excerpt
BACKGROUND: Nearly 10% of all pancreatic cancer (PCA) results from genetic predisposition. Although abnormalities in sporadic PCA have been described, little is known about the genetics of heritable PCA. The purpose of this study was to identify novel genes expressed in patients with a presumed genetic predisposition or "familial" PCA. PATIENTS AND METHODS: We defined "familial" PCA as patients having one or more...
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