HLA and Nasal Polyposis Susceptibility: A Meta-analysis of Worldwide Studies.

doi:10.1177/00034894241275476

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Article

HLA and Nasal Polyposis Susceptibility: A Meta-analysis of Worldwide Studies.

The Annals of otology, rhinology, and laryngology - 1 Nov 2024

Witcher Ryan, Anur Sugosh M, Thibaut Dylan, Venturino Luciano, Grube Jordon G

Abstract excerpt

OBJECTIVES: Nasal polyposis (NP) is a common and recurrent condition of the sinonasal cavity which has significant impact on patients' quality of life. NP pathophysiology involves a complex interplay of genetic, environmental, and immunological factors. Several studies have explored the association between human leukocyte antigen (HLA) class II alleles and NP, but the results have been conflicting. The aim of...

Topics

Humans
Genetic Predisposition to Disease
Nasal Polyps
HLA-DQ alpha-Chains
HLA-DRB1 Chains
Alleles
HLA-DQ beta-Chains

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Open in PubMed

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PMID: 39175144
DOI: 10.1177/00034894241275476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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