Article
[Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis].
Ontogenez - 1 Jan 2000
Ogienko A A, Karagodin D A, Fedorova S A, Fedorova E V, Lashina V V, Baricheva E M
Abstract excerpt
We generated and characterized a new hypomorphic mutation of Drosophila melanogaster Trithorax-like (Trl) gene named Trl362. The Trl362 homozygous females are sterile and lay a small number of eggs; most embryos die at the early developmental stages. The transcriptional Trl level of adult Trl362 females was markedly lowered. Little or no GAGA protein, encoded by Trl@, was detected in the nurse cell nuclei. The...
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