Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[RET and GFRA1 germline polymorphisms in medullary thyroid cancer patients].

Molekuliarnaia biologiia - 1 Jan 2000

Severskaia N V, Saenko V A, Il'in A A, Chebotareva I V, Rumiantsev P O, Isaev P A, Medvedev V S, Iasmita S

Abstract excerpt

The role of RET and GFRA1 germline polymorphisms in predisposition to sporadic medullary thyroid cancer (MTC) and polymorphisms' modulation effect on clinical features of inherited and sporadic MTC were investigated. Blood samples from 67 MTC patients (22 hereditary and 45 sporadic), 3 asymptomatic mutant RET gene carriers and 178 ethnically matched healthy control individuals were tested. Screening of RET exons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Medullary
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glial Cell Line-Derived Neurotrophic Factor Receptors

Share to Linkage Disequilibrium

Share to Neoplasm Proteins

Share to Polymorphism, Restriction Fragment Length

Share to Thyroid Neoplasms

Share to Time Factors

Source

Identifiers

PMID: 16813162

Genes

RET
GFRA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[RET and GFRA1 germline polymorphisms in medullary thyroid cancer patients].PMID 16813162Read ↗

[Genetic polymorphisms: implications in the pathogenesis of medullary thyroid carcinoma].Semantic proximity Read ↗

The frequency of selected polymorphic variants of the RET gene in patients with medullary thyroid carcinoma and in the general population of central Poland.Semantic proximity Read ↗

Molecular basis of medullary thyroid carcinoma: the role of RET polymorphisms.Semantic proximity Read ↗

[Proto-oncogene RET somatic mutations in medullary thyroid carcinoma].Semantic proximity Read ↗

Significance of the RET proto-oncogene polymorphisms in Turkish sporadic medullary thyroid carcinoma patients.Semantic proximity Read ↗

Evaluation of germline sequence variants of GFRA1, GFRA2, and GFRA3 genes in a cohort of Spanish patients with sporadic medullary thyroid cancer.Semantic proximity Read ↗

Polymorphisms in the RET proto-oncogene and the phenotypic presentation of familial medullary thyroid carcinoma.Semantic proximity Read ↗

Medullary thyroid carcinoma (MTC) and RET proto-oncogene: mutation spectrum in the familial cases and a meta-analysis of studies on the sporadic form.Semantic proximity Read ↗

[Analysis of mutations in the RET proto-oncogene in patients with medullary thyroid tumor].Semantic proximity Read ↗

Analysis of RET polymorphisms and haplotypes in the context of sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid CarcinomaSemantic proximity Read ↗

Analysis of inherited genetic variants in ret proto-oncogene of Brazilian patients with apparently sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.