Article
Polymorphisms of the gene encoding cholesterol ester transfer protein and serum lipoprotein levels in subjects with and without coronary heart disease.
Human genetics - 1 Sept 1991
Tenkanen H, Koshinen P, Kontula K, Aalto-Setälä K, Mänttäri M, Manninen V, Runeberg S L, Taskinen M R, Ehnholm C
Abstract excerpt
We determined TaqI-A, TaqI-B and EcoNI genotypes at the cholesteryl ester transfer protein (CETP) locus in 111 healthy volunteers and in 187 hyperlipidemic men of whom 72 had suffered a myocardial infarction. There were no significant differences in the allele distributions at these polymorphic loci either between the population sample and the hyperlipidemic subjects, or between patients with and without previous...
Topics
- Adult
- Alleles
- Apolipoproteins
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Cholesterol Esters
- Female
- Gene Frequency
- Glycoproteins
- Humans
- Hyperlipidemias