Article
MUC4 gene polymorphism and expression in women with implantation failure.
Human reproduction (Oxford, England) - 1 Sept 2006
Koscinski Isabelle, Viville Stephane, Porchet Nicole, Bernigaud Annie, Escande Fabienne, Defossez Andre, Buisine Marie-Pierre
Abstract excerpt
INTRODUCTION: The molecular mechanism of human embryo implantation is poorly understood. The role of MUC4 mucin, present in endometrial epithelium, has never been explored, and results obtained in animal studies strongly suggest a role in implantation. We investigated the role of MUC4 in human embryo implantation. METHODS AND RESULTS: We analysed the MUC4 variable number of tandem repeat (VNTR) polymorphism in...
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