Article
MUC 1: a genetic susceptibility to infertility?
Lancet (London, England) - 28 Apr 2001
Horne A W, White J O, Margara R A, Williams R, Winston R M, Lalani E
Abstract excerpt
In man and some animals regulation of embryo implantation by endometrial expression of the highly polymorphic MUC 1 mucin has been suggested. We assessed the polymorphism of MUC 1 in women known to be fertile and those with infertility due to suspected failure of embryo implantation. The median of the lower allele size in the infertile group was only 2.5 kb compared with 3.4 kb in the fertile group (p=0.0029,...
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