Article
MUC4 gene polymorphisms associate with endometriosis development and endometriosis-related infertility.
BMC medicine - 24 Feb 2011
Chang Cherry Yin-Yi, Chang Hui-Wen, Chen Chih-Mei, Lin Chia-Ying, Chen Chih-Ping, Lai Chih-Ho, Lin Wei-Yong, Liu Hsing-Ping, Sheu Jim Jinn-Chyuan, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: Mucin 4 (MUC4) plays an important role in protecting and lubricating the epithelial surface of reproductive tracts, but its role in the pathogenesis of endometriosis is largely unknown. METHODS: To correlate MUC4 polymorphism with the risk of endometriosis and endometriosis-related infertility, we performed a case-control study of 140 patients and 150 healthy women. Six unique single-nucleotide...
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