Characterization of the functional domains of Escherichia coli RNase II.

Abstract excerpt

RNase II is a single-stranded-specific 3'-exoribonuclease that degrades RNA generating 5'-mononucleotides. This enzyme is the prototype of an ubiquitous family of enzymes that are crucial in RNA metabolism and share a similar domain organization. By sequence prediction, three different domains have been assigned to the Escherichia coli RNase II: two RNA-binding domains at each end of the protein (CSD and S1), and...

Topics

• Amino Acid Sequence
• Catalytic Domain
• Escherichia coli
• Exoribonucleases
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• Protein Conformation
• RNA, Bacterial
• RNA, Double-Stranded
• RNA-Binding Proteins
• Sequence Homology, Amino Acid