Article
Heteroduplex screening for molecular defects in factor IX genes from haemophilia B families.
British journal of haematology - 1 Feb 1995
Chen S H, Schoof J M, Weinmann A F, Thompson A R
Abstract excerpt
Heteroduplex screening of amplified fragments containing sequences of all known small haemophilic mutations in the factor IX gene localized mutations in 18 new families: 12 were at common recurrent sites; three were novel. Carriers and/or patients from each of 41 families with mutations in 7 exon...
Topics
- DNA
- Factor IX
- Genetic Carrier Screening
- Genetic Testing
- Hemophilia B
- Humans
- Mutation
- Nucleic Acid Heteroduplexes