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Article

A genetic analysis of 23 Chinese patients with hemophilia B.

Scientific reports - 25 Apr 2016

Wang Qing-Yun, Hu Bei, Liu Hui, Tang Liang, Zeng Wei, Wu Ying-Ying, Cheng Zhi-Peng, Hu Yu

Abstract excerpt

Hemophilia B (HB) is an X-linked recessive bleeding disorder caused by mutations in the coagulation factor IX (FIX) gene. Genotyping patients with HB is essential for genetic counseling and provides useful information for patient management. In this study, the F9 gene from 23 patients with HB was analyzed by direct sequencing. Nineteen point mutations were identified, including a novel missense variant...

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Identifiers

PMID: 27109384
DOI: 10.1038/srep25024
PMCID: PMC4842959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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