Article
Factor IX gene haplotypes in Brazilian blacks and characterization of unusual DdeI alleles.
British journal of haematology - 1 Aug 1994
Figueiredo M S, Bowen D J, Silva Júnior W A, Zago M A
Abstract excerpt
Analysis of factor IX gene polymorphisms is considered the best approach for prenatal diagnosis and carrier detection of haemophilia B when the identification of the gene mutation is not possible. Studies involving factor IX gene polymorphisms in Black populations are scarce and essentially restr...
Topics
- Alleles
- Black People
- Brazil
- DNA-Cytosine Methylases
- Factor IX
- Female
- Fetal Diseases
- Genetic Carrier Screening
- Genetic Linkage
- Haplotypes
- Hemophilia B
- Heterozygote
- Humans
- Male
- Polymorphism, Restriction Fragment Length
- Pregnancy
- Prenatal Diagnosis
- Sequence Analysis, DNA