Single-strand conformation polymorphism (SSCP) analysis of the molecular pathology of hemophilia B.

doi:10.1002/humu.1380020506

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Article

Single-strand conformation polymorphism (SSCP) analysis of the molecular pathology of hemophilia B.

Human mutation - 1 Jan 1993

David D, Rosa H A, Pemberton S, Diniz M J, Campos M, Lavinha J

Abstract excerpt

In the present study, we report the application of polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis to the screening of seven functionally important factor IX gene (FIX) regions (total length 2.66 kb) in 9 unrelated haemophilia B patients of Portuguese or Afri...

Topics

Base Sequence
DNA
DNA, Single-Stranded
Factor IX
Hemophilia B
Humans
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Polymerase Chain Reaction
Polymorphism, Genetic

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