Article
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer
1 Jan 2006
Abstract excerpt
Human kallikrein 6 (KLK6) was identified based on its transient upregulation in a primary breast tumor and its subsequent silencing in a metastatic tumor from the same patient. The molecular mechanism(s) underlying the deregulated expression of KLK6 during cancer progression are currently unknown. Here, we provide evidence that aberrant expression of KLK6 is regulated at the level of transcription by multiple...
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