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Article

The epigenetic basis for the aberrant expression of kallikreins in human cancers

1 Jan 2006

Abstract excerpt

The tissue kallikrein gene family consists of 15 genes tandemly arranged on human chromosome 19q13.4. Most kallikrein genes are characterized by aberrant expression patterns in various human cancers, a feature that makes them ideal cancer biomarkers. In the present study, we investigated the effect of the epigenetic drug compound 5-aza-2'-deoxycytidine on the expression of downregulated kallikrein genes in...

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Identifiers

PMID: 16800742
DOI: 10.1515/bc.2006.100

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