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Article

Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients.

Molecular cancer - 20 May 2015

Schrader Carola H, Kolb Markus, Zaoui Karim, Flechtenmacher Christa, Grabe Niels, Weber Klaus-Josef, Hielscher Thomas, Plinkert Peter K, Hess Jochen

Abstract excerpt

BACKGROUND: Dysregulated expression of Kallikrein-related peptidase 6 (KLK6) is a common feature for many human malignancies and numerous studies evaluated KLK6 as a promising biomarker for early diagnosis or unfavorable prognosis. However, the expression of KLK6 in carcinomas derived from mucosal epithelia, including head and neck squamous cell carcinoma (HNSCC), and its mode of action has not been addressed so...

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Source

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Identifiers

PMID: 25990935
DOI: 10.1186/s12943-015-0381-6
PMCID: PMC4437453

Genes

KLK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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