Article
Molecular genetic analysis of complete hydatidiform moles.
Cancer genetics and cytogenetics - 15 Jul 1991
Kovacs B W, Shahbahrami B, Tast D E, Curtin J P
Abstract excerpt
Complete hydatidiform moles (CHM) are the most common form of gestational trophoblastic disease and a frequent antecedent to choriocarcinoma. Cytogenetic investigations into the origin of these tumors have shown that they can arise by virtue of unusual fertilization events. In this study we used molecular genetic "fingerprinting" methods to examine the genome of 22 consecutive CHM in order to determine their...
Topics
- Alleles
- DNA Fingerprinting
- Fathers
- Female
- Humans
- Hydatidiform Mole
- Mothers
- Polymorphism, Restriction Fragment Length
- Pregnancy