Article
Genetics of gestational trophoblastic disease.
Best practice & research. Clinical obstetrics & gynaecology - 1 Jul 2021
Fisher Rosemary A, Maher Geoffrey J
Abstract excerpt
The abnormal pregnancies complete and partial hydatidiform mole are genetically unusual, being associated with two copies of the paternal genome. Typical complete hydatidiform moles (CHMs) are diploid and androgenetic, while partial hydatidiform moles (PHMs) are diandric triploids. While diagnosis can usually be made on the basis of morphology, ancillary techniques that exploit their unusual genetic origin can be...
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