Article
Association between alleles of the transforming growth factor-alpha locus and the occurrence of cleft lip.
American journal of medical genetics - 1 Mar 1993
Sassani R, Bartlett S P, Feng H, Goldner-Sauve A, Haq A K, Buetow K H, Gasser D L
Abstract excerpt
DNA samples from 100 patients with cleft lip with or without cleft palate (CL/P) were compared with those of 98 unaffected control individuals with respect to transforming growth factor alpha (TGFA) genotypes. Among the Caucasians in this population (83 CL/P, 84 controls), there was a significant difference in the restriction fragment length polymorphisms (RFLPs) observed after digestion with TaqI (chi 2 = 4.68,...
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