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Article

Immunostimulatory oligodeoxynucleotide from<i>Bifidobacterium longum</i>suppresses Th2 immune responses in a murine model

22 May 2006

Abstract excerpt

We have reported previously that novel immunostimulatory sequence (ISS) oligodeoxynucleotide (ODN) BL07S from a probiotic strain of Bifidobacterium longum inhibited immunoglobulin (Ig) E production in vitro. However, whether ISS-ODNs from probiotics regulate T helper type 2 (Th2)-polarized immune reactions in vivo remains unclear. To evaluate the inhibitory effects of ODN BL07S on type I allergic response, BALB/c...

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PMID: 16792683
DOI: 10.1111/j.1365-2249.2006.03111.x

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