Article
[Loss of Ha-ras alleles in DNA from gastric carcinoma tissue of Chinese individuals].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Jun 1991
Shan X
Abstract excerpt
In this study, a human c-Ha-ras-1 6 kilobase recombinant clone (EcoRI fragment) was used as a probe, DNA from 13 gastric carcinoma patients heterozygous for the Ha-ras locus contained two Ha-ras-related BamHI restriction fragments. Southern blotting results showed similar patterns of allelic restriction fragments between gastric carcinoma and normal gastric tissue DNA in 12 cases. But one heterozygous patient...
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