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Article

Vitamin D and estrogen receptor gene polymorphisms and the risk of colorectal cancer in Bulgaria.

International journal of colorectal disease - 1 Apr 2007

Kadiyska Tanya, Yakulov Toma, Kaneva Radka, Nedin Dimitar, Alexandrova Alexandrina, Gegova Antonina, Savov Alexey, Mitev Vanio, Kremensky Ivo

Abstract excerpt

BACKGROUND AND AIMS: Different epidemiological studies report the protective effect on colorectal cancer (CRC) exerted by vitamin D(3) intake, estrogen replacement therapy, and increase of the risk of microsatellite instability (MSI) in CRC by withdrawal of estrogens. The aim of our study was to search for association between CRC and polymorphisms in estrogen receptor-alpha (ER-alpha) and Vitamin D receptor (VDR)...

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Identifiers

PMID: 16788818
DOI: 10.1007/s00384-006-0163-0

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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