Article
Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jul 2006
Inoue Akira, Suzuki Takuji, Fukuhara Tatsuro, Maemondo Makoto, Kimura Yuichiro, Morikawa Naoto, Watanabe Hiroshi, Saijo Yasuo, Nukiwa Toshihiro
Abstract excerpt
PURPOSE: This study was undertaken to investigate the efficacy and the feasibility of gefitinib for chemotherapy-naïve patients with advanced non-small-cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations. PATIENTS AND METHODS: The EGFR gene status in various tumor samples obtained from chemotherapy-naïve advanced NSCLC patients was examined by DNA sequencing of EGFR exons 18 to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
