Article
EGFR mutation of tumor and serum in gefitinib-treated patients with chemotherapy-naive non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Mar 2006
Kimura Hideharu, Kasahara Kazuo, Shibata Kazuhiko, Sone Takashi, Yoshimoto Akihiro, Kita Toshiyuki, Ichikawa Yukari, Waseda Yuko, Watanabe Kazuyoshi, Shiarasaki Hiroki, Ishiura Yoshihisa, Mizuguchi Masayuki, Nakatsumi Yasuto, Kashii Tatsuhiko, Kobayashi Masashi, Kunitoh Hideo, Tamura Tomohide, Nishio Kazuto, Fujimura Masaki, Nakao Shinji
Abstract excerpt
BACKGROUND: The authors evaluate the efficacy and safety of gefitinib monotherapy in chemotherapy-naive patients with advanced non-small-cell lung cancer (NSCLC). A secondary endpoint is to evaluate the relationship between clinical manifestations and epidermal growth factor receptor (EGFR) mutation status. METHODS: Japanese chemotherapy-naive NSCLC patients were enrolled. They had measurable lesions, Eastern...
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