Article
Gefitinib for non-small-cell lung cancer treatment.
Expert opinion on drug safety - 1 Nov 2011
D'Incecco Armida, Cappuzzo Federico
Abstract excerpt
INTRODUCTION: Gefitinib is an EGFR tyrosine kinase inhibitor (EGFR-TKI) that demonstrated efficacy in patients with advanced non-small cell lung cancer (NSCLC) across therapy lines. In the first-line setting, recent randomized Phase III trials comparing EGFR-TKIs versus platinum-based doublets demonstrated that in patients harboring an activating EGFR mutation, gefitinib is superior to chemotherapy in terms of...
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