Article
Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas.
The American journal of surgical pathology - 1 Feb 2006
Adeniran Adebowale J, Zhu Zhaowen, Gandhi Manoj, Steward David L, Fidler James P, Giordano Thomas J, Biddinger Paul W, Nikiforov Yuri E
Abstract excerpt
Papillary carcinoma is the most common type of thyroid malignancy. It has been recently shown that these tumors commonly have one of three genetic alterations: BRAF point mutations, RET/PTC rearrangements, or RAS point mutations. In this study, we analyze the relationship between these alterations and the microscopic features of papillary carcinomas, their clinical features, and prognostic characteristics....
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