Article
Comparison of skin esterase activities from different species.
Pharmaceutical research - 1 Jul 2006
Prusakiewicz Jeffery J, Ackermann Chrisita, Voorman Richard
Abstract excerpt
PURPOSE: Many topically applied drugs contain esters that are hydrolyzed in the skin. Minipigs have emerged as potential models of human dermatology and, in some aspects, may be superior to commonly used rat skin. The aims of this study were to evaluate the suitability of minipig and rat skin as in vitro models of human epidermal esterase activity. METHODS: Naphthyl acetate and para-nitrophenyl acetate were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
