Article
DAZ gene copies: evidence of Y chromosome evolution.
Molecular human reproduction - 1 Aug 2006
Fernandes Ana Teresa, Fernandes Susana, Gonçalves Rita, Sá Rosália, Costa Paula, Rosa Alexandra, Ferrás Cristina, Sousa Mário, Brehm António, Barros Alberto
Abstract excerpt
The DAZ gene, a contributing factor in infertility, lies on the human Y chromosome's AZFc region, whose deletion is a common cause of spermatogenic failure. Y chromosome binary polymorphisms on the non-recombining Y (NRY) region, believed to be a single occurrence on an evolutionary scale, were typed in a sample of fertile and infertile men with known DAZ backgrounds. The Y single-nucleotide polymorphisms...
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