Article
Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.
Human molecular genetics - 1 Sept 1998
Agulnik A I, Zharkikh A, Boettger-Tong H, Bourgeron T, McElreavey K, Bishop C E
Abstract excerpt
The recent transposition to the Y chromosome of the autosomal DAZL1 gene, potentially involved in germ cell development, created a unique opportunity to study the rate of Y chromosome evolution and assess the selective forces that may act upon such genes, and provided a new estimate of the male-t...
Topics
- Africa
- Animals
- Base Sequence
- Biological Evolution
- Cercopithecidae
- Conserved Sequence
- DNA Primers
- DNA Transposable Elements
- Deleted in Azoospermia 1 Protein
- Female
- Genetic Linkage
- Genetic Variation
- Humans
- Male
- Models, Genetic