Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transplantation of Human Embryonic Stem Cell-Derived Pancreatic Endoderm Reveals a Site-Specific Survival, Growth, and Differentiation

4 Apr 2012

Abstract excerpt

Development of β-cells from human embryonic stem cells (hESCs) could compensate for the shortage of islet donors required for diabetes therapy. Although pancreatic progenitors have been derived from hESCs using various protocols, no fully functional b-cells could be generated in vitro. We evaluated the in vivo growth and differentiation of PDX1+ pancreatic endoderm cells obtained from hESCs. Here we show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22472700
DOI: 10.3727/096368912x636812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transplantation of Human Embryonic Stem Cell-Derived Pancreatic Endoderm Reveals a Site-Specific Survival, Growth, and DifferentiationPMID 22472700Read ↗

Endoderm and Pancreatic Islet Lineage Differentiation from Human Embryonic Stem CellsSemantic proximity Read ↗

Generation of Insulin-Producing Islet-Like Clusters from Human Embryonic Stem CellsSemantic proximity Read ↗

Translational embryology: Using embryonic principles to generate pancreatic endocrine cells from embryonic stem cellsSemantic proximity Read ↗

Directed Differentiation of Human Embryonic Stem Cells into the Pancreatic Endocrine LineageSemantic proximity Read ↗

Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In VivoSemantic proximity Read ↗

Functional Beta Cell Mass from Device-Encapsulated hESC-Derived Pancreatic Endoderm Achieving Metabolic ControlSemantic proximity Read ↗

Recent Advances and Prospects in the Differentiation of Pancreatic Cells From Human Embryonic Stem CellsSemantic proximity Read ↗

Insulin-Producing Cells Derived from Human Embryonic Stem Cells: Comparison of Definitive Endoderm- and Nestin-Positive Progenitor-Based Differentiation StrategiesSemantic proximity Read ↗

Biphasic Induction of Pdx1 in Mouse and Human Embryonic Stem Cells Can Mimic Development of Pancreatic β-CellsSemantic proximity Read ↗

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineagesSemantic proximity Read ↗

Endoderm induction for hepatic and pancreatic differentiation of ES cells.Semantic proximity Read ↗

Differentiation of Mouse Embryonic Stem Cells into Endoderm without Embryoid Body FormationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.