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Article

Neural tube derived signals and Fgf8 act antagonistically to specify eye versus mandibular arch muscles.

Development (Cambridge, England) - 1 Jul 2006

von Scheven Gudrun, Alvares Lúcia E, Mootoosamy Roy C, Dietrich Susanne

Abstract excerpt

Recent knockout experiments in the mouse generated amazing craniofacial skeletal muscle phenotypes. Yet none of the genes could be placed into a molecular network, because the programme to control the development of muscles in the head is not known. Here we show that antagonistic signals from the neural tube and the branchial arches specify extraocular versus branchiomeric muscles. Moreover, we identified Fgf8 as...

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PMID: 16775000
DOI: 10.1242/dev.02426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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