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Article

CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis.

European journal of clinical pharmacology - 1 Jun 2006

Vuilleumier Nicolas, Rossier Michel F, Chiappe Alberto, Degoumois Florence, Dayer Pierre, Mermillod Bernadette, Nicod Laurent, Desmeules Jules, Hochstrasser Denis

Abstract excerpt

OBJECTIVE: To determine whether pharmacogenetic tests such as N-acetyltransferase 2 (NAT2) and cytochrome P450 2E1 (CYP2E1) genotyping are useful in identifying patients prone to antituberculosis drug-induced hepatotoxicity in a cosmopolite population. METHODS: In a prospective study we genotyped...

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Share to Antitubercular Agents
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemical and Drug Induced Liver Injury

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Share to Isoniazid

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Source

Identifiers

PMID: 16770646
DOI: 10.1007/s00228-006-0111-5

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16770646-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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