Article
Concordant association of lipid gene variation with a combined HDL/LDL-cholesterol phenotype in two European populations.
Human heredity - 1 Jan 2006
Bauerfeind Anja, Knoblauch Hans, Costanza Michael C, Luganskaja Tatjana, Toliat Mohammad R, Nürnberg Peter, Luft Friedrich C, Reich Jens G, Morabia Alfredo
Abstract excerpt
OBJECTIVE: SNP/phenotype associations are difficult to validate. This comparative study demonstrates significant contribution of candidate genes to the variation of a complex cholesterol phenotype, measured in two general populations by a gene-based approach. METHODS: Independent samples of normolipidemic subjects from two Caucasian populations (371 Swiss and 157 Germans) were selected for a case-control-study...
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