Article
Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.
Journal of lipid research - 1 Sept 2006
Vaessen Stefan F C, Schaap Frank G, Kuivenhoven Jan-Albert, Groen Albert K, Hutten Barbara A, Boekholdt S Matthijs, Hattori Hiroaki, Sandhu Manjinder S, Bingham Sheila A, Luben Robert, Palmen Jutta A, Wareham Nicholas J, Humphries Steve E, Kastelein John J P, Talmud Philippa J, Khaw Kay-Tee
Abstract excerpt
In mouse models, apolipoprotein A-V (apoA-V) exhibits triglyceride (TG)-lowering effects. We investigated the apoA-V/TG relationship and the association of apoA-V with coronary artery disease (CAD) risk by determining serum apoA-V levels and genotypes in a nested case-control (n = 1,034/2,031) study. Both univariate and multivariate apoA-V levels showed no association with future CAD (P = 0.4 and 0.5,...
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