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Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix

9 Jun 2006

Abstract excerpt

Here we report a human-derived material with potent inductive activity that selectively converts ES cells into neural tissues. Both mouse and human ES cells efficiently differentiate into neural precursors when cultured on the matrix components of the human amniotic membrane in serum-free medium [amniotic membrane matrix-based ES cell differentiation (AMED)]. AMED-induced neural tissues have regional...

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PMID: 16766664
DOI: 10.1073/pnas.0600104103

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