Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Origin of mutations under selection: the adaptive mutation controversy.

Annual review of microbiology - 1 Jan 2006

Roth John R, Kugelberg Elisabeth, Reams Andrew B, Kofoid Eric, Andersson Dan I

Abstract excerpt

Growth under selection causes new genotypes to predominate in a population. It is difficult to determine whether selection stimulates formation of new mutations or merely allows faster growth of mutants that arise independent of selection. In the practice of microbial genetics, selection is used to detect and enumerate pre-existing mutants; stringent conditions prevent growth of the parent and allow only the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Nucleic Acid Amplification Techniques

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Recombination, Genetic

Share to Selection, Genetic

Share to Sigma Factor

Source

Identifiers

PMID: 16761951
DOI: 10.1146/annurev.micro.60.080805.142045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Origin of mutations under selection: the adaptive mutation controversy.PMID 16761951Read ↗

The Origin of Mutants Under Selection: How Natural Selection Mimics Mutagenesis (Adaptive Mutation).Semantic proximity Read ↗

Adaptive mutation: the uses of adversity.Semantic proximity Read ↗

Adaptive amplification and point mutation are independent mechanisms: evidence for various stress-inducible mutation mechanisms.Semantic proximity Read ↗

Identifying Targets of Selection in Laboratory Evolution Experiments.Semantic proximity Read ↗

The spectrum of adaptive mutations in experimental evolution.Semantic proximity Read ↗

Profiling the initial burst of beneficial genetic diversity in clonal cell populations to anticipate evolutionSemantic proximity Read ↗

Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number.Semantic proximity Read ↗

Quantifying stochastic establishment of mutants in microbial adaptation.Semantic proximity Read ↗

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment.Semantic proximity Read ↗

Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation.Semantic proximity Read ↗

Experimental evolution, loss-of-function mutations, and "the first rule of adaptive evolution".Semantic proximity Read ↗

Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.