Article
Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells.
The Journal of general virology - 1 Jul 2006
Spiegel Martin, Schneider Kerstin, Weber Friedemann, Weidmann Manfred, Hufert Frank T
Abstract excerpt
Severe acute respiratory syndrome (SARS) of humans is caused by a novel coronavirus of zoonotic origin termed SARS-associated coronavirus (SARS-CoV). The virus induces severe injury of lung tissue, as well as lymphopenia and destruction of the architecture of lymphatic tissue by as-yet-unknown mechanisms. In this study, the interaction of SARS-CoV with dendritic cells (DCs), the key regulators of immune...
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