Article
Structural and functional characterization of the zebrafish lamin B receptor.
European journal of cell biology - 1 Aug 2006
Schild-Prüfert Kristina, Giegerich Marieke, Schäfer Matthias, Winkler Christoph, Krohne Georg
Abstract excerpt
The lamin B receptor (LBR) is an integral membrane protein of the inner nuclear membrane that is interacting with B-type lamins, chromatin and DNA. The complete loss of the protein in mouse mutants causes a reduced viability of embryos, and viable animals develop abnormalities of the skeleton. Here, we present the molecular characterization of the zebrafish LBR (zLBR) gene and the functional analysis of LBR...
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