Article
Robo3 isoforms have distinct roles during zebrafish development.
Mechanisms of development - 1 Oct 2005
Challa Anil K, McWhorter Michelle L, Wang Chunping, Seeger Mark A, Beattie Christine E
Abstract excerpt
Roundabout (Robo) receptors and their secreted ligand Slits have been shown to function in a number of developmental events both inside and outside of the nervous system. We previously cloned zebrafish robo orthologs to gain a better understanding of Robo function in vertebrates. Further characterization of one of these orthologs, robo3, has unveiled the presence of two distinct isoforms, robo3 variant 1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.