Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical significance of overexpression of multiple RND-family efflux pumps in Bacteroides fragilis isolates.

The Journal of antimicrobial chemotherapy - 1 Sept 2006

Pumbwe Lilian, Chang Abraham, Smith Rachel L, Wexler Hannah M

Abstract excerpt

OBJECTIVES: The aim of the present study was to determine correlation between bmeB efflux pump overexpression and resistance to fluoroquinolones and beta-lactams in Bacteroides fragilis clinical isolates (n = 51) and the effects of broad-spectrum efflux pump inhibitors (EPIs) on the MICs of the test antibiotics. METHODS: Susceptibility to garenoxacin, levofloxacin, moxifloxacin, cefoxitin and faropenem +/- EPIs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacteroides fragilis

Share to Drug Resistance, Multiple, Bacterial

Share to Gene Expression Regulation, Bacterial

Share to Membrane Transport Proteins

Share to Microbial Sensitivity Tests

Share to Mutation

Source

Identifiers

PMID: 16840432
DOI: 10.1093/jac/dkl278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical significance of overexpression of multiple RND-family efflux pumps in Bacteroides fragilis isolates.PMID 16840432Read ↗

Bacteroides fragilis BmeABC efflux systems additively confer intrinsic antimicrobial resistance.Semantic proximity Read ↗

Identification of antimicrobial resistance genes in multidrug-resistant clinical Bacteroides fragilis isolates by whole genome shotgun sequencingSemantic proximity Read ↗

Antibiotic resistance pattern of Bacteroides fragilis isolated from clinical and colorectal specimensSemantic proximity Read ↗

Comparative Genomics of Bacteroides fragilis Group Isolates Reveals Species-Dependent Resistance Mechanisms and Validates Clinical Tools for Resistance PredictionSemantic proximity Read ↗

Phenotypic and genotypic correlation of antimicrobial susceptibility of Bacteroides fragilis: lessons learntSemantic proximity Read ↗

RAPID MULTIPLEX PCR ASSAY FOR SIMULTANEOUS DETECTION OF MAJOR ANTIBIOTIC RESISTANCE DETERMINANTS IN CLINICAL ISOLATES OF BACTEROIDES FRAGILISSemantic proximity Read ↗

Emergence and evolution of an international cluster of MDR Bacteroides fragilis isolates.Semantic proximity Read ↗

Molecular cloning of the gyrA and gyrB genes of Bacteroides fragilis encoding DNA gyrase.Semantic proximity Read ↗

gyrA mutations associated with quinolone resistance in Bacteroides fragilis group strains.Semantic proximity Read ↗

Fosfomycin resistance inAcinetobacter baumanniiis mediated by efflux through a major facilitator superfamily (MFS) transporter—AbaFSemantic proximity Read ↗

Sixteen homologs of the mex-type multidrug resistance efflux pump in Bacteroides fragilis.Semantic proximity Read ↗

AdeR-AdeS mutations & overexpression of the AdeABC efflux system in ciprofloxacin-resistant Acinetobacter baumannii clinical isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.