Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of the human D-glyceric acidemia related glycerate kinase gene GLYCTK1 and its alternatively splicing variant GLYCTK2.

DNA sequence : the journal of DNA sequencing and mapping - 1 Feb 2006

Guo Jin-Hu, Hexige Saiyin, Chen Li, Zhou Guang-Jin, Wang Xiang, Jiang Jian-Min, Kong Ya-Hui, Ji Guo-Qing, Wu Chao-Qun, Zhao Shou-Yuan, Yu Long

Abstract excerpt

Deficiency of human glycerate kinase leads to D-glycerate acidemia/D-glyceric aciduria. Through PCR cloning assisted by in silico approach, we isolated the human glycerate kinase genes--Glycerate Kinase 1 (GLYCTK1) and its alternatively splicing variant--Glycerate Kinase 2 (GLYCTK2), which might be associated with D-glycerate acidemia/D-glyceric aciduria. The locus of GLYCTK gene is mapped to 3p21. PCR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to In Situ Hybridization

Share to In Situ Hybridization, Fluorescence

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Protein Isoforms

Share to Tissue Distribution

Source

Identifiers

PMID: 16753811
DOI: 10.1080/10425170500476665

Genes

GLYCTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of the human D-glyceric acidemia related glycerate kinase gene GLYCTK1 and its alternatively splicing variant GLYCTK2.PMID 16753811Read ↗

D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK).Semantic proximity Read ↗

Identification of a novel glucokinase mutation in an Indian woman with GCK-MODY.Semantic proximity Read ↗

Structure, Mutation, Functional Domain Roles and Medical Implications of Glycerol Kinase.Semantic proximity Read ↗

Glycerol kinase deficiency in adults: Description of 4 novel cases, systematic review and development of a clinical diagnostic score.Semantic proximity Read ↗

TGM2 and implications for human disease: role of alternative splicingSemantic proximity Read ↗

Human glucokinase regulatory protein (GCKR): cDNA and genomic cloning, complete primary structure, and chromosomal localizationSemantic proximity Read ↗

Current status and progress of research on the ADP-dependent glucokinase geneSemantic proximity Read ↗

A yeast with muscle doesn’t run faster: full humanization of the glycolytic pathway in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

A second locus encoding elevated phosphoglycerate mutase activity (Pgam2e) maps to mouse chromosome 4.Semantic proximity Read ↗

Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants.Semantic proximity Read ↗

Human glutamate pyruvate transaminase (GPT): localization to 8q24.3, cDNA and genomic sequences, and polymorphic sites.Semantic proximity Read ↗

Identification of the Human Mnk2 Gene (MKNK2) through Protein Interaction with Estrogen Receptor βSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.