Article
Human glutamate pyruvate transaminase (GPT): localization to 8q24.3, cDNA and genomic sequences, and polymorphic sites.
Genomics - 1 Mar 1997
Sohocki M M, Sullivan L S, Harrison W R, Sodergren E J, Elder F F, Weinstock G, Tanase S, Daiger S P
Abstract excerpt
Two frequent protein variants of glutamate pyruvate transminase (GPT) (E.C.2.6.1.2) have been used as genetic markers in humans for more than two decades, although chromosomal mapping of the GPT locus in the 1980s produced conflicting results. To resolve this conflict and develop useful DNA marke...
Topics
- Alanine Transaminase
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 8
- DNA, Complementary
- Exons
- Genes
- Genetic Variation
- Humans
- Isoenzymes
- Microsatellite Repeats
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
- Rats
- Sequence Analysis, DNA