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Article

ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients.

Pharmacogenomics - 1 Jun 2006

Seo Takayuki, Ishitsu Takateru, Ueda Nao, Nakada Naoyuki, Yurube Keigo, Ueda Kentaro, Nakagawa Kazuko

Abstract excerpt

OBJECTIVES: The efflux transporter P-glycoprotein encoded by the ATP-binding cassette (ABC)B1 gene may play a role in drug-resistant epilepsy by limiting gastrointestinal absorption and brain access of antiepileptic drugs (AEDs). Our objective was to investigate the effect of ABCB1 polymorphisms...

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Share to Anticonvulsants
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16753003
DOI: 10.2217/14622416.7.4.551

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16753003-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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