Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common variants in MODY genes increase the risk of gestational diabetes mellitus.

Diabetologia - 1 Jul 2006

Shaat N, Karlsson E, Lernmark A, Ivarsson S, Lynch K, Parikh H, Almgren P, Berntorp K, Groop L

Abstract excerpt

AIMS/HYPOTHESIS: Impaired beta cell function is the hallmark of gestational diabetes mellitus (GDM) and MODY. In addition, women with MODY gene mutations often present with GDM, but it is not known whether common variants in MODY genes contribute to GDM. SUBJECTS AND METHODS: We genotyped five common variants in the glucokinase (GCK, commonly known as MODY2), hepatocyte nuclear factor 1-alpha (HNF1A, commonly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes, Gestational
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucokinase

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Hepatocyte Nuclear Factor 4

Share to Linkage Disequilibrium

Share to Pregnancy

Share to Sweden

Source

Identifiers

PMID: 16752173
DOI: 10.1007/s00125-006-0258-8

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common variants in MODY genes increase the risk of gestational diabetes mellitus.PMID 16752173Read ↗

Genetics of gestational diabetes mellitus.Semantic proximity Read ↗

Mutations in GCK and HNF-1alpha explain the majority of cases with clinical diagnosis of MODY in Spain.Semantic proximity Read ↗

Identification of novel GCK and HNF1A/TCF1 mutations and polymorphisms in German families with maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Association of Common Genetic Risk Variants With Gestational Diabetes Mellitus and Their Role in GDM Prediction.Semantic proximity Read ↗

Nine novel mutations in maturity-onset diabetes of the young (MODY) candidate genes in 22 Spanish families.Semantic proximity Read ↗

Variants in MODY genes associated with maternal lipids profiles in second trimester of pregnancy.Semantic proximity Read ↗

Clinical application of ACMG-AMP guidelines in HNF1A and GCK variants in a cohort of MODY families.Semantic proximity Read ↗

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY).Semantic proximity Read ↗

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes MellitusSemantic proximity Read ↗

Novel single nucleotide polymorphisms in gestational diabetes mellitus.Semantic proximity Read ↗

Tunisian Maturity-Onset Diabetes of the Young: A Short Review and a New Molecular and Clinical Investigation.Semantic proximity Read ↗

Hemoglobin A1C can differentiate subjects with GCK mutations among patients suspected to have MODY.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.