Article
Tunisian Maturity-Onset Diabetes of the Young: A Short Review and a New Molecular and Clinical Investigation.
Frontiers in endocrinology - 1 Jan 2021
Moalla Mariam, Safi Wajdi, Babiker Mansour Maab, Hadj Kacem Mohamed, Mahfood Mona, Abid Mohamed, Kammoun Thouraya, Hachicha Mongia, Mnif-Feki Mouna, Hadj Kacem Faten, Hadj Kacem Hassen
Abstract excerpt
Introduction/Aims: Maturity-Onset Diabetes of the Young (MODY) is a monogenic non-autoimmune diabetes with 14 different genetic forms. MODY-related mutations are rarely found in the Tunisian population. Here, we explored MODY related genes sequences among seventeen unrelated Tunisian probands qualifying the MODY clinical criteria. Materials and Methods: The GCK and HNF1A genes were systematically analyzed by...
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