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Article

Hyphal invasion of Candida albicans inhibits the expression of human beta-defensins in experimental oral candidiasis.

The Journal of investigative dermatology - 1 Sept 2006

Lu Qian, Jayatilake Jayalath A M S, Samaranayake Lakshman P, Jin Lijian

Abstract excerpt

Oral epithelium reacts to microbial challenges by eliciting a defensive response that includes the production of antimicrobial peptides. This study investigated the expression of human beta-defensins-1, 2, and 3 in reconstituted human oral epithelia during experimental oral infections with six different Candida species, and a wild-type C. albicans isolate and five of its mutants. The expression of defensins was...

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Identifiers

PMID: 16741514
DOI: 10.1038/sj.jid.5700346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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