Article
Lack of association between the aggrecan gene and familial idiopathic scoliosis.
Spine - 1 Jun 2006
Marosy Beth, Justice Cristina M, Nzegwu Nneka, Kumar Gunjan, Wilson Alexander F, Miller Nancy H
Abstract excerpt
STUDY DESIGN: A study was conducted to determine the potential association between a specific aggrecan gene polymorphism and familial idiopathic scoliosis (FIS). OBJECTIVES: To determine the allelic distribution of the exon 12 polymorphism within a sample of families with FIS. SUMMARY OF BACKGROUND DATA: FIS is a structural curvature of the spine where the underlying genetic etiology has not been established. The...
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