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Article

Inherited Thrombophilia: Implications for Prevention and Treatment of Venous Thromboembolism

1 Oct 2009

Abstract excerpt

Inherited thrombophilia, defined as a genetically determined tendency to develop venous thromboembolism (VTE), contributes to the pathogenesis of approximately 40% of VTE episodes. About 50% of carriers of inherited thrombophilic traits develop VTE, but the impact of the different abnormalities is variable in terms of clinical penetrance. Some rare abnormalities (natural anticoagulant deficiencies, homozygous...

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Share to Blood Coagulation and Thrombosis Mechanisms
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PMID: 20013535
DOI: 10.1055/s-0029-1242722

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