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Article

Molecular crowding increases the amplification success of multiple displacement amplification and short tandem repeat genotyping.

Analytical biochemistry - 15 Aug 2006

Ballantyne Kaye N, van Oorschot Roland A H, Mitchell R John, Koukoulas Irene

Abstract excerpt

Multiple displacement amplification (MDA) can generate large quantities of genomic DNA product from small amounts of template. We investigated the ability of MDA to amplify samples containing very small amounts of target DNA (5 pg to 1 ng) in the presence of a second, larger DNA sample for downstream short tandem repeat (STR) multiplex genotyping. We observed that STR amplification success of the minor fraction...

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Identifiers

PMID: 16737679
DOI: 10.1016/j.ab.2006.04.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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