Article
Diversity among DRw13 DQw7 haplotypes as revealed by serology Dw typing and restriction fragment length polymorphism.
Human immunology - 1 Feb 1991
Gebuhrer L, Freidel A C, Lambert J, Labonne M P, Farre A, Betuel H
Abstract excerpt
HLA-DRw13 is in linkage disequilibrium with DQw6; an unusual association, DRw13 DQw7, is found in 2% of our Caucasoid population. Investigation of genotyped individuals and of families by two allosera and by Dw typing revealed two subtypes: one recognized by homozygous typing cell HAG and by two allosera, the other subtype remained unreactive with both reagents. Analysis of DNA fragments with DNA probes indicated...
Topics
- Genetic Variation
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DR Serological Subtypes
- Haplotypes
- Humans
- Polymorphism, Restriction Fragment Length